894 Poly(I:C) and GAG inhibit exogenous HSV1 infection in the barrier dysfunctional 3D epidermal model
نویسندگان
چکیده
منابع مشابه
Dysfunctional 3D model based on structural and neuropsychological information
M. Luna Serrano , R. Caballero Hernández , L. M. González Rivas , A. García Molina, A. García Rudolph, C. Cáceres, R. Sánchez Carrión, T. Roig Rovira, J.M. Tormos Muñoz, E.J. Gómez Aguilera 2 Bioengineering and Telemedicine Centre, ETSI Telecomunicación, Universidad Politécnica de Madrid, Av. Complutense 30, 28040, Madrid, Spain. 2 Biomedical Research Networking Center in Bioengineering, Biomat...
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Two families of G protein-coupled receptors of the neurotransmitter dopamine, i.e., dopamine 1-like family (D1-like receptor) and dopamine 2-like family (D2-like receptor), show dopaminergic activity in nerve cells. The D2-like receptor family, composed of D2, D3, and D4 receptors, downregulates the intracellular cAMP signaling pathway, and dopamine receptor agonists reduce the cAMP level in ne...
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15 صفحه اولEpidermal Barrier in Atopic Dermatitis
Atopic dermatitis (AD) is a complex disease that affects up to 20% of children and impacts the quality of patients and families in a significant manner. New insights into the pathophysiology of AD point to an important role of structural abnormalities in the epidermis combined with immune dysregulation. Filaggrin (FLG) is synthesized as a large precursor, profilaggrin, and is expressed in the u...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2018
ISSN: 0022-202X
DOI: 10.1016/j.jid.2018.03.906